John Curry Spikes (July 22, 1881 – June 28, 1955) was an American jazz musician, composer, and entrepreneur from Dallas, Texas. Alongside his brother, Reb Spikes, John ran a traveling show band in the early 1900s, which included the legendary Jelly Roll Morton. The Spikes brothers performed in San Francisco around 1915 under the name The Original So-Different Orchestra, with Reb Spikes being promoted as the "World's Greatest Saxophonist."

In 1919, the brothers settled in Los Angeles, where they established a music store, a nightclub, a talent agency, and a publishing house. They were pioneers in the jazz recording industry, being the first to record an all-black jazz band in 1922. In 1927, they produced a short sound film that predated the release of The Jazz Singer, the first full-length sound film. John Spikes is also noted for his contributions to jazz standards, having co-written the lyrics to Jelly Roll Morton's "Wolverine Blues" and composing "Someday Sweetheart," which remains a jazz classic.