Lloyd "Tiny" Grimes (July 7, 1916 – March 4, 1989) was an influential American jazz and R&B guitarist known for his work with the electric tenor guitar, a four-stringed instrument. Born in Newport News, Virginia, Grimes initially played drums and piano before switching to the electric guitar in 1938. By 1940, he had joined the Cats and the Fiddle as a guitarist and singer. His career took a significant turn when he joined the Art Tatum Trio from 1943 to 1944, contributing to the group's classic recordings.

Grimes led his own recording session in 1944, featuring the legendary Charlie Parker, producing tracks such as "Tiny's Tempo" and "Red Cross." He later formed the Rockin’ Highlanders, an R&B-oriented group known for performing in kilts and featuring notable musicians like Red Prysock and Screamin’ Jay Hawkins. This group achieved success with a jazzed-up version of "Loch Lomond."

Throughout his career, Grimes recorded for various labels, including Blue Note, Prestige, and Black & Blue, and collaborated with artists like Coleman Hawkins and Billie Holiday. He was also part of the first Moondog Coronation Ball in 1952, considered the first rock and roll concert. Grimes remained active in the music scene until his death in New York City from meningitis in 1989. His contributions to jazz and early rock and roll, along with his unique playing style, have left a lasting impact on the music world.