The Billy May Orchestra, led by Edward William "Billy" May Jr., was a prominent ensemble in the mid-20th century, known for its distinctive big band sound. Billy May, born on November 10, 1916, in Pittsburgh, Pennsylvania, was a celebrated composer, arranger, and trumpeter. He initially gained recognition during the Big Band era, working with notable figures like Charlie Barnet and Glenn Miller. May's arrangement of "Cherokee" for Barnet became a significant hit and a key inspiration for the bebop movement.

In the 1950s, May formed his own orchestra, which became known for its unique orchestral arrangements and compositions. The orchestra released several successful albums, including hits like "Charmaine" and "Lean Baby." May's signature "slurping saxophones" sound became a hallmark of his music, contributing to his popularity.

Throughout his career, May collaborated with many top singers, including Frank Sinatra, Nat King Cole, and Peggy Lee, and worked extensively with Capitol Records. His orchestra was also featured in numerous children's projects and film and television scores, such as The Green Hornet and Batman.

Despite his success, May was known for his humorous and easygoing nature, which endeared him to many in the music industry. His contributions to music spanned over six decades, leaving a lasting impact on the big band and orchestral music scenes. Billy May passed away on January 22, 2004, in San Juan Capistrano, California, leaving behind a rich legacy of musical innovation and collaboration.